Project 1 - Jessica Z.K. Caldwell, PhD

Specific Aims:

1. Establish the relationship between neuropsychological tests results to findings on resting state fMRI in the AD continuum (mild cognitive impairment [MCI], mild to moderate AD) in comparison with cognitively normal controls (CNC)
2. Establish the relationship between neuropsychological test scores and neuroimaging biomarkers of inflammation (microglial imaging) in patients with diagnoses of AD and PD