Project R-2 – Dr. Samantha John
Ethnoracial Characterization of Patient-Centered Outcomes
Dr. Samantha John
Project 2 will evaluate clinical trial outcome measures and characterize patient-centered outcomes in neurodegenerative disease within non-Hispanic white, Hispanic, and Black/African American participants. Improving the identification and assessment of Alzheimer’s disease and other neurodegenerative disorders across diverse populations is a public health priority. Accurate and inclusive disease diagnosis requires reliable and culturally valid patient outcome measures. Patient-centered outcomes also increase the likelihood of patient engagement and retention in research. Project 2 utilizes an exploratory sequential mixed-methods design to:
- evaluate the measurement properties of existing clinical trial outcome measures across ethnoracial groups
- identify culturally sensitive healthcare concerns and prioritized patient-centered outcomes
- compare healthcare perceptions and preferences within and across groups
The findings from this study have profound impact for clinical trials and outcome measurement among older adults with neurodegenerative disease.